Fig. 1

Modulation of protein p53 and HDAC5 expression in HCC after RT. Following radiation exposure at 2 Gy and 4 Gy, protein expression of p53, P21, and HDAC5 were confirmed by western blot in a time-dependent manner up to 24 h per 6 h (A-F). The expression of each protein was quantified based on b-actin levels. Data are shown as mean ± SEM of three independent experiments. *P < 0.05, **P < 0.01, and ***P < 0.001 vs. untreated by Student’s t-test